Cerebral amebiasis due to Acanthamoeba sp. in a patient with complete gp91 phox deficiency

Journal of Human Immunity 2026 Open access

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Authors: Marie Roelens, Anna‐Lena Neehus, Jérémie Rosain, Gislène Collobert, Nathalie Boddaert, Liana Carausu, Jacinta Bustamante
DOI: 10.70962/jhi.20250160
Cited by: 2
References: 5

Abstract

A patient diagnosed with chronic granulomatous disease due to complete gp91phox deficiency developed multiple cerebral abscesses caused by Acanthamoeba species. This case highlights that invasive parasitic infections can reveal underlying phagocytic defects and underscores for prompt immunological and genetic evaluation in such situations.

Fields of Study & Subjects

Legionella and Acanthamoeba research Neutrophil Myeloperoxidase and Oxidative Mechanisms Amoebic Infections and Treatments

Publication details

Journal / source
Journal of Human Immunity
Publisher
Rockefeller University Press
Volume
2
Issue
3
Pages
e20250160–e20250160
Publication date
12 February 2026
Language
EN