Weiqi Decoction （胃祺饮） alleviates chronic atrophic gastritis by regulating abnormalities in gastric mucosal cell proliferation and apoptosis
Abstract
目的 探讨胃祺饮加减对慢性萎缩性胃炎（CAG）患者胃黏膜上皮细胞异常增殖与凋亡的改善作用。 方法 采用免疫组化法检测对照组（10例萎缩性胃炎患者、10例浅表性胃炎患者）及治疗组（61例胃祺饮加减治疗患者）胃黏膜组织中PCNA、p21、p53、Caspase-3、cytochrome c、COX-2、NF-κB的表达情况，TUNEL法检测细胞凋亡情况，并结合病理改变行统计学分析。 结果 与浅表性胃炎患者的胃黏膜上皮相比，慢性萎缩性胃炎患者胃黏膜上述7种指标表达及细胞凋亡均显著高于浅表性胃炎（P
Fields of Study & Subjects
Helicobacter pylori-related gastroenterology studies
Traditional Chinese Medicine Clinical Research
Gastric Cancer Management and Outcomes
Publication details
- Journal / source
- Lishizhen Medicine and Materia Medica Research
- Volume
- 37
- Issue
- 2
- Pages
- 257–262
- Publication date
- 1 January 2026
- Language
- EN