Research progress on the intervention of active components of traditional Chinese medicine in bladder cancer based on autophagy-related pathways
Abstract
膀胱癌(BCa)是常见的泌尿系统恶性肿瘤,细胞自噬是影响BCa病情进展的重要因素,作为BCa治疗的关键靶点目前备受学者关注。中药在防治BCa过程发挥至关重要的作用,此作用与癌细胞自噬之间关系并无明确定论。尽管目前已开展中药提取物调控细胞自噬干预BCa的诸多实验,但缺乏相关的全面评估。文章在阐述细胞自噬相关信号通路以及BCa与细胞自噬间联系的基础上,重点总结中药多种活性成分通过调控细胞自噬干预BCa的现状,分析各成分在自噬活动的作用,为BCa治疗提供了新的中医药视角。
Fields of Study & Subjects
Autophagy in Disease and Therapy
Bladder and Urothelial Cancer Treatments
Natural Compounds in Disease Treatment
Publication details
- Journal / source
- Lishizhen Medicine and Materia Medica Research
- Volume
- 37
- Issue
- 2
- Pages
- 312–320
- Publication date
- 1 January 2026
- Language
- EN