Research progress on the mechanism of Chinese herbal medicine in hyperpigmentation alleviation and skin whitening

Lishizhen Medicine and Materia Medica Research 2026 Open access

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Authors: Jiashan LI, Qiong YIN, Bin XIE, Longmei Li, Lihua Dong, Suping XIAO, Yuye ZHU, Yanqin XU, Meiyu CAO
DOI: 10.70976/j.1008-0805.szgygy-2026-0218
Cited by: 0

Abstract

中药祛斑美白在美容领域备受关注，文章综述了近年来中药祛斑美白作用机制的进展。多种中药通过抑制黑色素细胞增殖、抑制酪氨酸酶活性、调节黑色素合成与转运相关信号通路、抗氧化以及干预细胞因子网络等多途径发挥作用。如常见中药美白成分可直接作用于酪氨酸酶或影响其基因表达，干预黑色素小体从黑素细胞到角质形成细胞的转运过程。中药还凭借抗氧化特性减少自由基对黑色素细胞的刺激，并通过调节细胞因子，达到改善皮肤微环境的效果。这些研究成果为开发新型、高效且安全的中药祛斑美白产品提供了坚实的理论依据，也为深入探究中药在皮肤色素调节方面的应用开辟了新方向。

Fields of Study & Subjects

melanin and skin pigmentation Dermatologic Treatments and Research Melanoma and MAPK Pathways

Publication details

Journal / source
Lishizhen Medicine and Materia Medica Research
Volume
37
Issue
2
Pages
321–330
Publication date
1 January 2026
Language
EN