Catalyst-free cyclization of DBU with α,β-ynones: substituent-controlled divergence

Mendeleev Communications 2026

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Authors: Olga V. Petrova, Igor Alekseevich Ushakov, Boris Aleksandrovich Trofimov
DOI: 10.71267/mencom.7865
Cited by: 0
References: 11

Abstract

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) cyclizes with α,β-ynones under catalyst-free conditions (MeCN, 3 h) to give a mixture of isolable diverse fused heterocycles including [3 + 3]- and [4 + 2]-cycloadducts as well as DBU ring expansion products, 14- and 15-membered heterocyclic systems incorporating the pyridinone moiety, in 48-58

Fields of Study & Subjects

Catalytic Alkyne Reactions Synthesis of heterocyclic compounds Organic Chemistry Synthesis Methods

Publication details

Journal / source
Mendeleev Communications
Volume
36
Issue
2
Pages
171–173
Publication date
1 January 2026
Language
RU