Comparison of nonstoichiometric and Mg-containing calcium-deficient hydroxyapatites obtained by enzymatic synthesis

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Authors: Georgy Sergeyevich Mikhaylov, Irina Gerasimova, Daria-Maria V. Ratova, Ivan V. Mikheev, Olga I. Klein, Maria Grigor'evna Chernysheva, Gennadii Aleksandrovich Badun
Cited by: 2
References: 23

Abstract

Enzymatic synthesis of calcium phosphate in Tris buffer with MgCl2 results in a two-fold increase in product yield compared to synthesis in water. Although some calcium positions are substituted with magnesium, both samples are classified as depleted hydroxyapatite. The Mg-containing sample exhibits higher aggregation capacity at high concentrations, resulting in reduced antimicrobial activity against gram-positive Bacillus strains.

Fields of Study & Subjects

Bone Tissue Engineering Materials Magnesium Alloys: Properties and Applications Calcium Carbonate Crystallization and Inhibition

Publication details

Journal / source
Mendeleev Communications
Publisher
OOO Zhurnal "Mendeleevskie Soobshcheniya"
Volume
36
Issue
2
Pages
232–234
Publication date
1 January 2026
Language
RU