Three-component synthesis of new γ-piperidone-incorporating aza-14-crown-4 compounds
Abstract
New aza-14-crown-4 compounds incorporating γ-piperidone unit have been prepared through the three-component reaction between dialdehyde podand, a ketone with two active methylene groups, and ammonium acetate or 2-phenylethylamine as nitrogen sources. Based on X-ray study, configuration of the products has been determined as rac-1S,21R,22S,24R.
Fields of Study & Subjects
Supramolecular Chemistry and Complexes
Multicomponent Synthesis of Heterocycles
Organic Chemistry Synthesis Methods
Publication details
- Journal / source
- Mendeleev Communications
- Volume
- 36
- Issue
- 4
- Pages
- 460–462
- Publication date
- 1 January 2026
- Language
- RU