Role of the RBMS Family in Different Cancers and Research Progress

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Authors: Hanchi Wu, Rui Hou, Yuhan Zhang, Hanfang Fan, Junying Xu, Huiyu Wang
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Abstract

RNA-binding proteins (RBPs), as posttranscriptional regulators, can modulate the activity and stability of target RNAs and participate in the whole life cycle of RNA processing, localization, modification and translation. RNA-binding motif single-stranded interacting proteins (RBMSs) comprise a critical subgroup within the RNA-binding protein (RBP) family, sharing the same domain characteristics as other RBPs. Several studies have shown that RBMSs can participate in tumorigenesis and tumor progression through mechanisms such as regulating the expression of oncogenes, growth factors and cell cycle proteins. In this paper, we reviewed the role of RBPs and related research progress in breast, prostate, lung, liver, gastric and colorectal cancers.

Fields of Study & Subjects

RNA Research and Splicing Cancer-related molecular mechanisms research RNA regulation and disease

Publication details

Journal / source
International Journal of Medical Sciences
Volume
23
Issue
3
Pages
804–814
Publication date
23 January 2026
Language
EN