Hyperglycemia in combination with excess fat intake promotes renal pyroptosis and fibrosis through Gα 12 -dependent endoplasmic reticulum stress

Theranostics 2026 Open access

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Authors: Muhammad Faizan Khan, Boram Kim, Yerim Jeon, Jihoon Tak, Yun Seok Kim, Sang Gil Lee, Eun Byul Lee, Chang-hoon Lee, Cheol Bin Eom, Hyun Sook Lee, Hyeon‐Ki Jang, NaKyeom Lee
+4 more Jeong Hae Kie, Jee Myung Yang, Yoon Mee Yang, Sang Geon Kim
DOI: 10.7150/thno.124015
Cited by: 3

Abstract

-mediated ER stress and inflammasome, delineating the mechanism underlying the conditions of diabetic renal complications and pharmacological intervention.

Fields of Study & Subjects

Inflammasome and immune disorders Chronic Kidney Disease and Diabetes Endoplasmic Reticulum Stress and Disease

Publication details

Journal / source
Theranostics
Publisher
Ivyspring International Publisher
Volume
16
Issue
8
Pages
3996–4018
Publication date
14 January 2026
Language
EN