Ligand-directed oral lipidic nanoplatform enables sustained ferroptosis and immune reprogramming via multivalent transporter-mediated metronomic delivery

Theranostics 2026 Open access

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Authors: Laxman Subedi, In Ho Im, Arjun Dhwoj Bamjan, Jiwon Jeon, Susmita Phuyal, Yunhwa Jeong, Seung Hyun Kim, Jung-Hyun Shim, Jeong Uk Choi, Jin Woo Park
DOI: 10.7150/thno.124189
Cited by: 2

Abstract

MCT-NE#9 enables a synergistic, low-toxicity chemo-immunotherapeutic strategy by sustaining ferroptosis and reprogramming the immune microenvironment via transporter-targeted oral delivery. This ligand-directed nanoplatform offers a clinically translatable approach for effective TNBC treatment.

Fields of Study & Subjects

Ferroptosis and cancer prognosis Immune cells in cancer Cancer Stress Anesthesia and Immune Response

Publication details

Journal / source
Theranostics
Publisher
Ivyspring International Publisher
Volume
16
Issue
6
Pages
2952–2983
Publication date
1 January 2026
Language
EN