ROS-sensitive liposomal co-delivery of photosensitizer, factor Xa inhibitor, and PD-L1 blockade enhances photodynamic immunotherapy

Theranostics 2026 Open access

Read full text
Authors: Yuhan Mai, Yanling Chen, Chao Li, Tongyao Wang, Shangli Ding, Hao Zhang, Haili Lin, Longguang Jiang, Cai Yuan, Xiaolei Zhou, Mingdong Huang, Peng Xu
DOI: 10.7150/thno.125408
Cited by: 0

Abstract

This study presents a strategy to amplify PDT-elicited immunotherapeutic efficacy by synergizing agents targeting distinct stages of the immune response. It also theoretically validates the synergy of PDT, anticoagulation therapy, and immune checkpoint inhibition in cancer treatment.

Fields of Study & Subjects

Photodynamic Therapy Research Studies Nanoplatforms for cancer theranostics Cancer Immunotherapy and Biomarkers

Publication details

Journal / source
Theranostics
Volume
16
Issue
8
Pages
4128–4146
Publication date
21 January 2026
Language
EN