Sono-piezoelectric cues regulate neuroinflammatory reflex-arc-mediated α7nAChR-P2RX7 axis to dampen osteoarthritis-correlated pain with osteoarthritis attenuation

Theranostics 2026 Open access

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Authors: Qiuling Zhong, Junqi Xie, Maocheng Zuo, Chuanan Liao, Qiuxia Peng, Simeng Yu, Pan Hu, Yuanyuan Liu, Li Zheng, Kun Zhang, Zhenhui Lu, Jinmin Zhao
DOI: 10.7150/thno.125686
Cited by: 3

Abstract

Our pioneering "sono-piezoelectrical signal-neural reflex-immunomodulation" cascade strategy for regulating neuroinflammatory reflex-arc-mediated α7nAChR-P2RX7 axis provide deep insights into OA-represented neuroinflammatory diseases.

Fields of Study & Subjects

Vagus Nerve Stimulation Research Cancer Stress Anesthesia and Immune Response Respiratory and Cough-Related Research

Publication details

Journal / source
Theranostics
Publisher
Ivyspring International Publisher
Volume
16
Issue
8
Pages
4358–4373
Publication date
30 January 2026
Language
EN