Nanotechnology-donated ischemic stroke therapeutics: evolving strategies from the basic to the cutting-edge

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Authors: Yuting Wang, Jiaxu Xu, Wenxuan Yan, Shenwu Zhang, Cong Luo, Yuequan Wang
Cited by: 3

Abstract

and facilitate BBB penetration. Specifically, thrombus- and cerebral ischemic lesion-targeted nano-DDS have emerged as a versatile toolbox for the precise treatment of IS. Herein, this paper provides an overview on the latest advancements in nano-DDS for IS therapy, covering conventional nanomedicines, cell membrane-camouflaged biomimetic nano-DDS, and exosome-involved nanotherapeutics, with a particular focus on the potential and application of cutting-edge nano-drug delivery techniques. Finally, we discuss the future perspectives and challenges of nano-DDS in the context of IS treatment.

Fields of Study & Subjects

Extracellular vesicles in disease Nanoparticle-Based Drug Delivery Neuroinflammation and Neurodegeneration Mechanisms

Publication details

Journal / source
Theranostics
Publisher
Ivyspring International Publisher
Volume
16
Issue
6
Pages
3173–3205
Publication date
1 January 2026
Language
EN