Near-infrared light-activated lidocaine microneedle patch for rapid local anesthesia
Abstract
Rationale: Effective local anesthesia with rapid onset and minimal invasiveness is essential for certain minor surgeries, such as aesthetic procedures, but remains difficult to achieve with conventional local anesthesia. Methods: studies were conducted to assess biosafety and invasiveness, while behavioral tests were performed in a rat plantar incision model to evaluate the onset and duration of anesthesia. Results: studies. Conclusions: The LiH/MXene@MNs platform offers an efficient, minimally invasive, and safe alternative to traditional local anesthesia techniques. This approach holds strong potential for use in minimally invasive aesthetic procedures, providing a promising solution for rapid and effective pain management.
Fields of Study & Subjects
Advancements in Transdermal Drug Delivery
Dental Anxiety and Anesthesia Techniques
Pediatric Pain Management Techniques
Publication details
- Journal / source
- Theranostics
- Publisher
- Ivyspring International Publisher
- Volume
- 16
- Issue
- 10
- Pages
- 5259–5277
- Publication date
- 9 March 2026
- Language
- EN