Spontaneous Ecchymosis as Initial Presentation of Acquired Hemophilia A
Abstract
Hemophilia A, a deficiency of clotting factor VIII, can be congenital, presenting with joint bleeding in childhood, or acquired, a rare subtype presenting as spontaneous bleeding most commonly seen in older adult patients. This report outlines an older adult patient with no history of bleeding disorders who developed acute-onset spontaneous ecchymoses and was found to have acquired hemophilia A. This case demonstrates the importance of a broad differential diagnosis in ecchymoses in older adult patients that includes coagulation factor deficiencies despite a lack of hematologic history. Early diagnosis and treatment of hemophilia A with hemostatic control and inhibitor eradication are imperative to prevent life-threatening bleeding.
Fields of Study & Subjects
Hemophilia Treatment and Research
Platelet Disorders and Treatments
Case Reports on Hematomas
Publication details
- Journal / source
- Annals of Internal Medicine Clinical Cases
- Volume
- 5
- Issue
- 2
- Publication date
- 1 February 2026
- Language
- EN