Spontaneous Ecchymosis as Initial Presentation of Acquired Hemophilia A

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Authors: Lahari Ramagiri, Anna Farrell, Julie Kielt
Cited by: 0
References: 8

Abstract

Hemophilia A, a deficiency of clotting factor VIII, can be congenital, presenting with joint bleeding in childhood, or acquired, a rare subtype presenting as spontaneous bleeding most commonly seen in older adult patients. This report outlines an older adult patient with no history of bleeding disorders who developed acute-onset spontaneous ecchymoses and was found to have acquired hemophilia A. This case demonstrates the importance of a broad differential diagnosis in ecchymoses in older adult patients that includes coagulation factor deficiencies despite a lack of hematologic history. Early diagnosis and treatment of hemophilia A with hemostatic control and inhibitor eradication are imperative to prevent life-threatening bleeding.

Fields of Study & Subjects

Hemophilia Treatment and Research Platelet Disorders and Treatments Case Reports on Hematomas

Publication details

Journal / source
Annals of Internal Medicine Clinical Cases
Volume
5
Issue
2
Publication date
1 February 2026
Language
EN