Dementia: Clinical Challenges
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Dementia is a decline in cognition that leads to functional impairment. It is a syndrome rather than a specific disease—the most common types of dementia are Alzheimer disease, dementia attributed to vascular disease, Lewy body dementia, and frontotemporal dementia. Only 1% to 2% of patients presenting with dementia have a potentially reversible disorder, such as normal pressure hydrocephalus, medication-induced cognitive impairment, hypothyroidism, or major depression ( 1 ). The Alzheimer’s Association estimates that about 7 million Americans aged 65 or older are currently living with Alzheimer disease—that means about 1 in 9 people aged 65 or older has a diagnosis of …
Fields of Study & Subjects
Dementia and Cognitive Impairment Research
Neurological Disease Mechanisms and Treatments
Alzheimer's disease research and treatments
Publication details
- Journal / source
- Annals of Internal Medicine
- Volume
- 179
- Issue
- 5
- Pages
- 740–741
- Publication date
- 16 March 2026
- Language
- EN