Reviewer #2 (Public review): Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

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Abstract

Developmentally-based directed differentiation from cortical progenitors sets a foundation for in vitro mechanistic and therapeutic disease modeling, and toward regenerative neuronal repopulation and circuit repair.

Fields of Study & Subjects

Neurogenesis and neuroplasticity mechanisms Pluripotent Stem Cells Research Developmental Biology and Gene Regulation

Publication details

Publication date
27 January 2026