eLife Assessment: TRPV3 channel activity helps cortical neurons stay active during fever
Abstract
Developmental electrophysiological adaptations and heat-sensitive proteins, such as TRPV3, in cortical excitatory neurons help maintain stable activity levels when brain temperature rises by 2–3°C during fever.
Fields of Study & Subjects
Ion Channels and Receptors
Thermal Regulation in Medicine
Neural dynamics and brain function
Publication details
- Publication date
- 27 January 2026