Reviewer #3 (Public review): Dependence of contextual modulation in macaque V1 on interlaminar signal flow

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Abstract

The results by Zhu et al provide valuable insights into the representation of border ownership in area V1.They used neuropixel recording to demonstrate the clustering of border ownership, and compared cross-correlation functions between neurons in different layers to demonstrate that they depend on the type of stimulus.The strength of the evidence is solid but can be improved by performing additional analyses and addressing some concerns (as raised in the previous and current review), and accounting for the differences in classical and non-classical receptive field stimulation conditions.

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Publication date
6 January 2026