Author response: Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis

Nedaa Al-Jezani; Asmaa Affan; Catherine A. Leonard; Nabangshu Das; Luiz Gustavo Almeida; Daniel W Young; Anand Oliveira Masson; Antoine Dufour; PAUL T. SALO; Pam Railton; James Powell; Roman J. Krawetz

doi:10.7554/elife.103332.3.sa3

Author response: Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis

2026 Open access

Read full text

Authors: Nedaa Al-Jezani, Asmaa Affan, Catherine A. Leonard, Nabangshu Das, Luiz Gustavo Almeida, Daniel W Young, Anand Oliveira Masson, Antoine Dufour, PAUL T. SALO, Pam Railton, James Powell, Roman J. Krawetz

DOI: 10.7554/elife.103332.3.sa3

Cited by: 0

Abstract

CD47Hi synovial mesenchymal stem cells are identified as a functionally distinct sub-population that regenerates articular cartilage and reduces osteoarthritis severity in a preclinical joint injury model.

Fields of Study & Subjects

Osteoarthritis Treatment and Mechanisms Mesenchymal stem cell research Periodontal Regeneration and Treatments

Publication details

Publication date: 20 January 2026