Reviewer #1 (Public review): Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML

eLife 2026 Open access

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DOI: 10.7554/elife.104978.3.sa1
Cited by: 0

Abstract

A comprehensive single-cell atlas of AML uncovers regulatory networks and age-dependent molecular differences to advance the understanding of disease mechanisms and enable subtype-specific therapeutic strategies.

Fields of Study & Subjects

Acute Myeloid Leukemia Research Single-cell and spatial transcriptomics Retinoids in leukemia and cellular processes

Publication details

Journal / source
eLife
Publication date
11 February 2026
Language
EN