Reviewer #2 (Public review): Neutralizing human monoclonal antibodies that target the PcrV component of the type III secretion system of Pseudomonas aeruginosa act through distinct mechanisms

eLife 2026 Open access

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DOI: 10.7554/elife.105195.3.sa2
Cited by: 0

Abstract

Human antibodies isolated from cystic fibrosis patients against PscF and PcrV of the Pseudomonas aeruginosa Type 3 Secretion System reveal that anti-PcrV antibodies inhibit secretion through distinct mechanisms.

Fields of Study & Subjects

Bacterial biofilms and quorum sensing Monoclonal and Polyclonal Antibodies Research Escherichia coli research studies

Publication details

Journal / source
eLife
Publication date
17 February 2026
Language
EN