eLife Assessment: Aggregation-dependent epitope sequence and modification fingerprints of anti-Aβ antibodies
Abstract
Comprehensive residue-level mapping of amyloid-beta recognition reveals how sequence variants, post-translational modifications, and aggregation state shape antibody specificity, thereby guiding selection and development of therapeutic antibodies in Alzheimer’s disease.
Fields of Study & Subjects
Alzheimer's disease research and treatments
Monoclonal and Polyclonal Antibodies Research
vaccines and immunoinformatics approaches
Publication details
- Journal / source
- eLife
- Publication date
- 9 February 2026
- Language
- EN