Reviewer #1 (Public review): Material Damage to Multielectrode Arrays after Electrolytic Lesioning is in the Noise

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Abstract

This useful manuscript addresses a stability issue for long-term chronically implanted array recordings and electrolytic lesioning, which is relevant to both basic science and translational research.The authors provide a systematic scanning electron microscopy (SEM) of explanted arrays, evaluating electrode damage and sharing extensive datasets accessible through interactive plots.The strength of the evidence is solid, but it can be improved by performing additional analyses on complementary neurophysiology, functional, or histological data.

Fields of Study & Subjects

Neuroscience and Neural Engineering Deep Brain Stimulation and Movement Disorders EEG and Brain-Computer Interfaces

Publication details

Journal / source
eLife
Publication date
4 March 2026
Language
EN