eLife Assessment: Biologically informed cortical models predict optogenetic perturbations
Abstract
Multi area RNN models fitted to in-vivo cortical activity predict behavioral changes induced by optogenetic perturbations, if biologically informed connectivity constraints on the optogenetically targeted inhibitory neurons are applied.
Fields of Study & Subjects
Neural dynamics and brain function
Memory and Neural Mechanisms
Neuroscience and Neuropharmacology Research
Publication details
- Publication date
- 16 January 2026