Author response: CCDC32 stabilizes clathrin-coated pits and drives their invagination

Ziyan Yang; Changsong Yang; Zheng Huang; Peiliu Xu; Yueping Li; Lu Han; Linyuan Peng; Xiangying Wei; John E. Pak; Tatyana Svitkina; Sandra L. Schmid; Zhiming Chen

doi:10.7554/elife.107039.3.sa4

Author response: CCDC32 stabilizes clathrin-coated pits and drives their invagination

2026 Open access

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Authors: Ziyan Yang, Changsong Yang, Zheng Huang, Peiliu Xu, Yueping Li, Lu Han, Linyuan Peng, Xiangying Wei, John E. Pak, Tatyana Svitkina, Sandra L. Schmid, Zhiming Chen

DOI: 10.7554/elife.107039.3.sa4

Cited by: 0

Abstract

Live cell imaging and biochemical analyses reveal that CCDC32 interacts with AP2 to stabilize and drive invagination of clathrin-coated pits, and that clinical mutations disrupting this interaction cause cardio-facio-neuro-developmental syndrome.

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Publication date: 5 January 2026