Reviewer #3 (Public review): Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake
Abstract
Live imaging analyses in budding yeast reveal that calorie restriction and overexpression of the mRNA binding protein Ssd1 both block deleterious age-dependent iron uptake as a mechanism to extend lifespan.
Fields of Study & Subjects
Genetics
Aging
and Longevity in Model Organisms
Autophagy in Disease and Therapy
Fungal and yeast genetics research
Publication details
- Publication date
- 12 January 2026