Reviewer #1 (Public review): Contrasting roles for IKK regulated inflammatory signalling pathways for development and maintenance of type 1 and adaptive 𝛄δ T cells

This study reports important findings regarding the role of the NF-kB signaling pathway in the development and long-term survival of gamma delta T cells.The authors report disparate roles of IKK-dependent NF-kB activation in the development and long-term survival of gamma delta T cell subsets.The approach and methodology employed is convincing.This work will be of great interest to immunologists interested in innate-like T cell biology and in T cell development.