Author response: ANTIPODE Provides a Global View of Cell Type Homology and Transcriptomic Divergence in the Developing Mammalian Brain

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Authors: Matthew T. Schmitz, Jingwen W Ding, Sara Nolbrant, Reed McMullen, Chang Ki Kim, Bryan J. Pavlovic, Tomasz J Nowakowski, Trygve E. Bakken, Chun Ye, Alex A. Pollen
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References: 58

Abstract

eLife AssessmentThis valuable study is an approach to integrating and comparing single-cell genomics data across species.The evidence supporting the conclusions of this work is solid, and ANTIPODE presents an updated methodological approach to determining how gene expression at the cell-type level has evolved.Thus, ANTIPODE should provide broad utility to studies of comparative neurogenomics and be of use to neuroscientists and evolutionary biologists.

Fields of Study & Subjects

Single-cell and spatial transcriptomics Developmental Biology and Gene Regulation Genomics and Phylogenetic Studies

Publication details

Journal / source
eLife
Publication date
16 March 2026
Language
EN