Lipid balance and chemoresistance in cancer cells

eLife 2026 Open access

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Authors: Kaori Kanemaru, Yoshikazu Nakamura
DOI: 10.7554/elife.110231
Cited by: 0
References: 8

Abstract

A shift in the balance between two lipids - cholesterol and sphingomyelin - makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.

Fields of Study & Subjects

Cancer Lipids and Metabolism Sphingolipid Metabolism and Signaling Cancer Cells and Metastasis

Publication details

Journal / source
eLife
Volume
15
Publication date
12 January 2026
Language
EN