Author response: The interplay between biomolecular assembly and phase separation

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Authors: Giacomo Bartolucci, Ivar S. Haugerud, Thomas C. T. Michaels, Christoph A. Weber
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Abstract

The authors present an important theoretical framework that describes the interplay between liquid-liquid phase separation and protein aggregation within a mean-field model.This work will be of high interest to the biophysics and molecular biology communities, as it will help understand and analyse assembly within biomolecular condensates in cells or in-vitro.Major strengths of this convincing work are the consideration of aggregates with various dimensionality and the possibility for protein gelation.

Fields of Study & Subjects

RNA Research and Splicing Protein Structure and Dynamics Theoretical and Computational Physics

Publication details

Publication date
9 January 2026