Author response: The RNA-binding protein HuR modulates the expression of the disease-linked CCL2 rs1024611G-rs13900T haplotype

2026 Open access

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Authors: Feroz Akhtar, Joselin Hernandez Ruiz, Ya-Guang Liu, Roy G. Resendez, Denis Féliers, Liza D. Morales, Álvaro Díaz-Badillo, Donna M. Lehman, Rector Arya, Juan Carlos Lopez Alvarenga, John Blangero, Ravindranath Duggirala
+1 more Srinivas Mummidi
DOI: 10.7554/elife.93108.3.sa3
Cited by: 0

Abstract

Bioinformatics, RNA-protein interactions, and HuR-based functional studies demonstrated that the rs13900T allele modulates CCL2 transcript levels, providing a functional link between the CCL2 rs1024611G-rs13900T haplotype and disease susceptibility/progression.

Fields of Study & Subjects

RNA Research and Splicing Genetic Associations and Epidemiology RNA regulation and disease

Publication details

Publication date
14 January 2026