Reviewer #2 (Public Review): Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function
Abstract
The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
Fields of Study & Subjects
Mitochondrial Function and Pathology
Cancer
Hypoxia
and Metabolism
Cell death mechanisms and regulation
Publication details
- Publication date
- 29 January 2026