Author response: Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation)

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Authors: James B. Isbister, András Ecker, Christoph Pokorny, Sirio Bolaños‐Puchet, Daniela Egas Santander, Alexis Arnaudon, Omar Awile, Natalí Barros-Zulaica, Jorge Blanco Alonso, Elvis Boci, Giuseppe Chindemi, Jean-Denis Courcol
+30 more Tanguy Damart, Thomas Delemontex, Alexander Dietz, Gianluca Ficarelli, Mike Gevaert, Joni Herttuainen, Genrich Ivaska, Weina Ji, Daniel Keller, James Gonzalo King, Pramod Kumbhar, Samuel Lapere, Polina Litvak, Darshan Mandge, Eilif Benjamin Muller, Fernando Pereira, Judit Planas, Rajnish Ranjan, Maria Reva, Armando Romani, Christian Rössert, Felix Schuermann, Vishal Sood, Aleksandra Teska, Mustafa Anıl Tuncel, Wener Van Geit, Matthias Wolf, Henry Markram, Srikanth Ramaswamy, Michael Reimann
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Abstract

A general and open multiscale cortical model is presented which can be used by the community to study neural coding, spike sorting, plasticity, optogenetic and extracellular stimulation, local field potential, and electroencephalography.

Fields of Study & Subjects

Neural dynamics and brain function Undergraduate Neuroscience Education and Research Neuroscience and Neural Engineering

Publication details

Publication date
20 January 2026