Recurrent Status Epilepticus in an Adult With Spastic Quadriplegic Cerebral Palsy

Status epilepticus (SE) is a neurological emergency associated with high morbidity and mortality. Management of individuals with cerebral palsy (CP) presents unique challenges due to baseline neurological deficits, limited communication, and altered metabolism of antiepileptic drugs (AEDs). We report the case of a 22-year-old male with spastic quadriplegic CP and long-standing epilepsy who presented with recurrent generalized tonic-clonic seizures persisting for five hours despite medication compliance. His pre-existing neurological impairment complicated early recognition. A non-contrast CT brain ruled out intracranial hemorrhage, stroke, and infection. The patient was treated with intravenous diazepam and phenytoin, resulting in seizure cessation within two hours, and was discharged seizure-free after four days. This report highlights the importance of prompt diagnosis and timely escalation of treatment in SE in adults with CP. Multidisciplinary follow-up and caregiver education remain essential for long-term control and prevention of recurrence.