Successful Management of Meningitis and Sepsis Due to Multidrug-Resistant Elizabethkingia meningoseptica in an Infant

Cureus 2026 Open access

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Authors: Minat Allah Alhusami, Shahad Alshamsi, Amina Mujahid, Arun Jayaraman
DOI: 10.7759/cureus.101368
Cited by: 0
References: 16

Abstract

We report a case of a two-month-old male infant, born prematurely, who initially presented with fever, irritability, and elevated inflammatory markers. He was then diagnosed with Elizabethkingia meningoseptica meningitis and sepsis. Treatment included intravenous levofloxacin, ampicillin, and cefotaxime. Despite the bacterium’s multidrug resistance and high reported morbidity and mortality rates, the patient made a full recovery with no complications at discharge or follow-up. This case demonstrates the challenges in treating E. meningoseptica infections and highlights the potential clinical efficacy of antibiotic regimens that may not align with standard susceptibility testing.

Fields of Study & Subjects

Bacterial Infections and Vaccines Neonatal and Maternal Infections Infections and bacterial resistance

Publication details

Journal / source
Cureus
Volume
18
Issue
1
Pages
e101368–e101368
Publication date
12 January 2026
Language
EN