Mazabraud Syndrome: The Contribution of Interventional Physiatry in a Clinical Case With 10 Years of Evolution

Mazabraud syndrome is a rare condition characterized by fibrous dysplasia and intramuscular myxomas. We present the case of a 66-year-old woman with chronic lumbosacral pain and imaging findings consistent with this syndrome, confirmed by biopsy. After years of conservative management with stable lesions but persistent symptoms, she underwent fluoroscopy-guided radiofrequency neurotomy of sacroiliac innervation, achieving complete pain relief and functional recovery. The patient was followed for five months after the intervention, with sustained symptom control and functional improvement. This case illustrates the diagnostic challenge and underscores the novelty of a targeted, minimally invasive interventional approach for symptom control in Mazabraud syndrome.