Correlation Between Ultrasound and Nerve Conduction Study Findings in Evaluating Carpal Tunnel Syndrome

Background Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy, caused by median nerve compression within the carpal tunnel, leading to pain, numbness, and functional impairment. Nerve conduction studies (NCS) remain the diagnostic gold standard, while ultrasonography (US) offers a non-invasive complementary modality. This study evaluated the correlation and agreement between US and NCS in CTS. Methodology In this cross-sectional study conducted at Dhaka Medical College Hospital from August 2021 to September 2022, 48 symptomatic patients (one hand per patient) underwent standardized NCS (motor distal latency (mDL), amplitude (mAMP), velocity (mCV), sensory distal latency (sDL), amplitude (sAMP), velocity (sCV)) and US at the inlet using a 16-MHz linear probe, with the sonographer blinded to clinical and NCS findings. CTS severity was graded by Bland's scale (NCS) and cross‑sectional area (CSA) thresholds (US). Spearman correlation assessed associations and Cohen's kappa quantified inter-modality agreement, with significance set at p-values