Open-Angle Glaucoma Presenting as Delayed-Onset Interface Fluid Syndrome in a Patient With Minimal Risk Factors

A 24-year-old male underwent uncomplicated myopic laser-assisted in situ keratomileusis (LASIK) three years prior to presentation to our clinic for left eye blurry vision. On initial examination, fluid was noted at the LASIK flap interface, with an elevated intraocular pressure (IOP) in the left eye. His pressure remained high despite treatment with multiple topical IOP-lowering agents, and visual field and retinal nerve fiber layer (RNFL) testing showed glaucomatous damage. He was subsequently referred to a glaucoma specialist and underwent surgical implantation of a glaucoma drainage device in the left eye, with postoperative stabilization of vision and IOP. This case is unique due to the patient's age, the long latency period between LASIK and symptom onset, and the absence of typical predisposing risk factors for glaucoma or interface fluid syndrome (IFS). This report highlights the importance of regular IOP monitoring in postoperative LASIK patients and urges providers to have a low threshold for completing glaucoma testing in atypical cases of IFS.