Systematized Linear Porokeratosis With Palmoplantar and Nail Involvement: A Rare Presentation
Abstract
Porokeratosis encompasses a group of genetically and clinically heterogenous dermatoses characterized by abnormal epidermal keratinization, with the cornoid lamella being the hallmark histological feature. Linear porokeratosis, a rare variant of porokeratosis, typically manifests early in life, with lesions that follow the lines of Blaschko and carry the highest risk of malignancy transformation. Here, we present a case of systematized linear porokeratosis in a 48-year-old male with childhood onset, notable for the rare co-existence of palmoplantar and nail involvement. This report emphasizes the importance of long-term surveillance in patients with linear porokeratosis due to its malignant potential.
Fields of Study & Subjects
Genetic and rare skin diseases.
Cancer and Skin Lesions
Porphyrin Metabolism and Disorders
Publication details
- Journal / source
- Cureus
- Volume
- 18
- Issue
- 2
- Pages
- e103504–e103504
- Publication date
- 12 February 2026
- Language
- EN