Subcutaneous Granuloma Annulare in a Middle-Aged Patient: A Case Report

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Authors: Yao Liang, Raj Patel, Douglas J. Grider, Padma V Chitnavis
Cited by: 0
References: 10

Abstract

Subcutaneous granuloma annulare (SGA) is a rare, benign variant of granuloma annulare, typically seen in children, which presents as asymptomatic subcutaneous nodules with normal overlying skin. The etiology remains unclear despite associations with systemic disease such as diabetes mellitus. Clinicopathologic correlation is crucial to accurate diagnosis. In this report, we present a case of a 53-year-old female patient with tender, bilateral subcutaneous nodules on her elbows. Punch biopsy confirmed the diagnosis of granuloma annulare. The primary management for her condition at the time was focused on observation and conservative care. However, secondary management with intralesional injection of triamcinolone was utilized when her lesions recurred after a window of resolution. Our case highlights an interesting manifestation of granuloma annulare and demonstrates the importance of both clinical and histological evaluation in distinguishing between similar presenting differential diagnoses. Successful treatment is heavily dependent on accurate diagnosis and patients should be monitored for complete resolution.

Fields of Study & Subjects

Skin Diseases and Diabetes Soft tissue tumors and treatment Autoimmune and Inflammatory Disorders

Publication details

Journal / source
Cureus
Volume
18
Issue
2
Pages
e103506–e103506
Publication date
12 February 2026
Language
EN