Detection of Latent Tuberculosis in Chronic Kidney Disease (CKD) Patients on Dialysis Using the Cy-TB Test: A Hospital-Based Cross-Sectional Study

Background Latent tuberculosis infection (LTBI) represents a major health burden in chronic kidney disease (CKD) patients on hemodialysis due to severe immunosuppression. Current diagnostic methods have limitations in this population. The Cy-TB test is a novel immunological assay for detecting TB infection, but its performance in patients with CKD undergoing dialysis is unknown. Objectives The primary objective was to estimate the prevalence of LTBI in CKD patients on maintenance hemodialysis using the Cy‑TB skin test and to describe its agreement with interferon‑gamma release assay (IGRA) among Cy‑TB-positive cases. Secondary objectives were to identify clinical and demographic factors associated with Cy‑TB positivity and to explore whether the early dialysis phase (