Difficulties in Diagnosing Gastric Adenocarcinoma of the Cervix: A Clinical Case and Literature Review

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Authors: Eduardo González‐Bosquet, Santiago González, Laia Ortiz Peidro, Sousa Cacheiro P, Leornardo A Rojo Muchacho
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References: 20

Abstract

We present the case of a 58-year-old patient diagnosed with gastric-type endocervical adenocarcinoma, a rare type of cervical cancer not associated with human papillomavirus (HPV) infection. The diagnosis was prompted by the incidental finding of endometrial thickening (9 mm) during a routine check-up for urinary incontinence. Hysteroscopic endometrial biopsy raised suspicion for malignancy, and further evaluation with serum CA 19-9 tumor marker and computed tomography confirmed the cervical origin of the tumor. The disease was diagnosed at an advanced stage, and despite primary treatment with chemoradiotherapy, the tumor recurred. We also provide a review of the literature focusing on the diagnostic challenges, treatment strategies, and prognosis of this rare form of cervical cancer.

Fields of Study & Subjects

Endometrial and Cervical Cancer Treatments Cervical Cancer and HPV Research Metastasis and carcinoma case studies

Publication details

Journal / source
Cureus
Volume
18
Issue
2
Pages
e104304–e104304
Publication date
26 February 2026
Language
EN