Difficulties in Diagnosing Gastric Adenocarcinoma of the Cervix: A Clinical Case and Literature Review
Abstract
We present the case of a 58-year-old patient diagnosed with gastric-type endocervical adenocarcinoma, a rare type of cervical cancer not associated with human papillomavirus (HPV) infection. The diagnosis was prompted by the incidental finding of endometrial thickening (9 mm) during a routine check-up for urinary incontinence. Hysteroscopic endometrial biopsy raised suspicion for malignancy, and further evaluation with serum CA 19-9 tumor marker and computed tomography confirmed the cervical origin of the tumor. The disease was diagnosed at an advanced stage, and despite primary treatment with chemoradiotherapy, the tumor recurred. We also provide a review of the literature focusing on the diagnostic challenges, treatment strategies, and prognosis of this rare form of cervical cancer.
Fields of Study & Subjects
Endometrial and Cervical Cancer Treatments
Cervical Cancer and HPV Research
Metastasis and carcinoma case studies
Publication details
- Journal / source
- Cureus
- Volume
- 18
- Issue
- 2
- Pages
- e104304–e104304
- Publication date
- 26 February 2026
- Language
- EN