Secondary Cardiac Rhabdomyosarcoma: A Unique Presentation

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Authors: Hibat Allah Kamri, Youssef Daoudi, O. Taoussi, Loubna Hamich, Hajar Rabii, Hicham Benyoussef, Amal El Ouarradi, Said Makani, Nabil Ismaili, Chafik El Kettani, Abdeltif Boulahya, Rachida Habbal
+1 more Fatimazahra Merzouk
Cited by: 0
References: 9

Abstract

Cardiac tumors are rare and complex, with malignant forms carrying a poor prognosis. These tumors are classified as either primary or secondary, with the latter, including metastases, being more prevalent. Rhabdomyosarcoma, a rare but aggressive soft tissue sarcoma, can occasionally metastasize to the heart. Here, we report the case of a 75-year-old male with metastatic rhabdomyosarcoma originating in the fibular muscles, extending to the left atrium, left ventricle, and bronchi. The patient presented with acute dyspnea, palpitations, and cardiogenic shock. Imaging revealed a large intracardiac mass, and urgent surgical resection was performed, followed by adjuvant chemoradiotherapy. The histopathological examination confirmed the diagnosis of rhabdomyosarcoma. Despite the poor prognosis typically associated with metastatic rhabdomyosarcoma, the patient showed clinical improvement post-surgery and continued treatment. This case highlights the aggressive nature of rhabdomyosarcoma with cardiac involvement and underscores the importance of multimodal management, including surgery and adjuvant therapy, to improve patient outcomes.

Fields of Study & Subjects

Cardiac tumors and thrombi Sarcoma Diagnosis and Treatment Cardiomyopathy and Myosin Studies

Publication details

Journal / source
Cureus
Volume
18
Issue
2
Pages
e104322–e104322
Publication date
26 February 2026
Language
EN