Keratinizing Squamous Cell Carcinoma Masquerading as Basal Cell Carcinoma Constituting a Diagnostic Pitfall: A Case Report With Etiopathogenetic Discourse and Mohs Micrographic Surgical Management

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Authors: Sanjoy Sanyal, Rachel Andrew, Delia Graham-Durand, Suhas Kotbagi, Bernadette Austrie
Cited by: 0
References: 5

Abstract

Among non-melanoma skin cancers of the face, basal cell carcinomas (BCC) and squamous cell carcinomas (SCC) are the most common. They are close differentials of each other and often constitute diagnostic pitfalls during assessment. This is a case report of the diagnosis and Mohs surgical management of an SCC that was initially clinically diagnosed as BCC. Mohs micrographic surgery (MMS) for cancers of cosmetically sensitive areas such as the face has proved to be a very useful procedure for ensuring 100% tumor removal with maximum normal tissue-sparing. This case report also analyzes the etiological, environmental, and demographic factors that lead to skin cancers of the face, with emphasis on the relationship of Fitzpatrick skin types and ultraviolet (UV) solar radiation vis-à-vis their propensity to cause skin cancers. High index of suspicion followed by early intervention still remains the hallmark of early, accurate diagnosis of skin cancers of the face, with the aim of ensuring high cure rates and minimum facial disfigurements. A case series of this type with longer follow-ups will alleviate the limitations of this case report.

Fields of Study & Subjects

Nonmelanoma Skin Cancer Studies Cancer and Skin Lesions Head and Neck Cancer Studies

Publication details

Journal / source
Cureus
Volume
18
Issue
2
Pages
e104371–e104371
Publication date
27 February 2026
Language
EN