Effect of Residual Insulin Secretion on Glycaemic Control Among Young Cameroonian Individuals With Type 1 Diabetes

Cureus 2026 Open access

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Authors: Mesmin Dehayem Yefou, Marcelle Nourya Meli Ymelong, Martine Claude Etoa Etoga, Agoons Batakeh, Jean-Claude Njabou Katte, Charly Feutseu, Anne Boli, Eugene Sobngwi
DOI: 10.7759/cureus.104502
Cited by: 1
References: 13

Abstract

Objective The objective of the article is to determine the effect of residual insulin secretion on glycaemic control among young Cameroonian individuals diagnosed with type 1 diabetes (T1D). Methods We conducted a hospital-based cross-sectional study from April to August 2022. Forty-two children and adolescents diagnosed with T1D attending the paediatric diabetes clinic of the Yaoundé Central Hospital in Cameroon were enrolled in the study. Residual insulin secretion was assessed by measuring plasma C-peptide concentrations before and after a mixed meal tolerance test (MMTT) using an enzyme-linked immunosorbent assay (ELISA) method. Glycosylated haemoglobin (HbA1c) was measured by boronate affinity chromatography with the HemoCue® HbA1c 501 analyser. Residual insulin secretion was classified as absent (

Fields of Study & Subjects

Diabetes Management and Research Diabetes Cardiovascular Risks and Lipoproteins Biological Research and Disease Studies

Publication details

Journal / source
Cureus
Publisher
Springer Science and Business Media LLC
Volume
18
Issue
3
Pages
e104502–e104502
Publication date
1 March 2026
Language
EN