A Rare Case of Levetiracetam-Induced Hemolytic Anemia

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Authors: Pedro Gil de Rubio Cruz, Dorimar Morales Torres, Karolane A Gonzalez Gonzalez
Cited by: 0
References: 6

Abstract

This is the case of a 77-year-old female patient with Alzheimer's disease, complicated by partial complex seizures. Levetiracetam was administered, which provoked hemolytic anemia. An extensive laboratory evaluation was suggestive of a non-immune etiology. Subsequent discontinuation of levetiracetam resulted in improvement of hemoglobin. Pancytopenia has been reported with the use of levetiracetam, but not isolated anemia. With this case report, we want to increase awareness of a potentially serious adverse reaction provoked by levetiracetam, a preferred anticonvulsive drug in the geriatric population.

Fields of Study & Subjects

Pharmacovigilance and Adverse Drug Reactions Drug-Induced Adverse Reactions Epilepsy research and treatment

Publication details

Journal / source
Cureus
Volume
18
Issue
3
Pages
e105064–e105064
Publication date
11 March 2026
Language
EN