Dilute Hyaluronic Acid for Lipoatrophy: Three Cases and Literature Review

Cureus 2026 Open access

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Authors: Juliana M O'Reilly, David S Kirwin, Travis Frantz, Willis Lyford
DOI: 10.7759/cureus.105227
Cited by: 2
References: 14

Abstract

Localized lipoatrophy, characterized by subcutaneous fat loss, can result from trauma, injectable drugs, panniculitis, or idiopathic causes, leading to outcomes ranging from self-resolution to permanent disfigurement. This case series presents a novel approach using dilute hyaluronic acid (HA) for three cases of lipoatrophy (trauma-induced, radiation-induced, and steroid-induced), with all cases showing notable improvement after one session. This approach represents a promising, low-risk alternative for managing lipoatrophy of various etiologies, with potential benefits for patient quality of life.

Fields of Study & Subjects

Dermatological and COVID-19 studies Body Contouring and Surgery Facial Rejuvenation and Surgery Techniques

Publication details

Journal / source
Cureus
Publisher
Springer Science and Business Media LLC
Volume
18
Issue
3
Pages
e105227–e105227
Publication date
14 March 2026
Language
EN