Medication-Related Osteonecrosis of the Jaw in a Patient With Prostate Cancer: A Case Presentation With a One-Month Follow-Up
Abstract
Medication-related osteonecrosis of the jaw (MRONJ) is an adverse event that most commonly occurs in patients undergoing bisphosphonate therapy and remains a significant challenge for dentists. Its clinical presentation varies according to the stages of the disease, depending on clinical and radiological findings. We report the case of an 81-year-old man presenting with a cutaneous fistula and purulent drainage from the lower right side of the mandible. The patient was under chemotherapy and receiving zoledronic acid treatment, administered as an intravenous injection every six months for 10 years. Oral manifestations of MRONJ can present with diverse lesions requiring careful clinical evaluation, accurate diagnosis, and appropriate management.
Fields of Study & Subjects
Bone health and treatments
Oral health in cancer treatment
Parathyroid Disorders and Treatments
Publication details
- Journal / source
- Cureus
- Publisher
- Springer Science and Business Media LLC
- Volume
- 18
- Issue
- 6
- Pages
- e110302–e110302
- Publication date
- 5 June 2026
- Language
- EN