Angiomyxolipoma of Right Cheek: A Rare Case Report

A lipoma is a benign tumour of adipose tissue and is the most common soft-tissue tumour in adults. It is typically a wellencapsulated, slow-growing, painless mass composed of mature fat cells. Lipomas can develop anywhere in the body, but they are most frequently found in the arms, shoulders, back, neck, and thighs. Angiomyxolipoma (AML) is a very rare variant of lipoma that consists of an admixture of adipose and myxoid elements with numerous vascular structures. Hereby, the authors present a case of a 56-year-old male who presented with a solitary swelling in the right cheek that had been present for the last two years. The Fine Needle Aspiration Cytology (FNAC) findings showed a few bland spindle cells along with some areas of dilated benign cells with elongated nuclei. Histopathological examination revealed a well-encapsulated tumour composed of mature adipose and myxoid tissues, along with blood vessels, confirming the diagnosis of AML of the right cheek. AML is a rare, benign soft-tissue tumour composed of adipose, myxoid, and vascular components. It is considered a variant of lipoma and is typically slow-growing, painless, and well-circumscribed. As of recent literature, fewer than 20 cases of AML have been reported in the English medical literature. Due to their rarity and histological overlap with other myxoid and vascular-rich tumours, such as myxoid liposarcoma or angiomyxoma, accurate diagnosis is crucial. Immunohistochemical staining and careful histopathological evaluation are essential to distinguish AML from other entities.